
As we navigate different stages of life, our health needs evolve. Hormone Replacement Therapy (HRT) is a topic that often sparks curiosity, and sometimes concern. While commonly associated with menopause symptom relief, HRT offers long-term health benefits that go beyond managing hot flashes and night sweats. However, like any treatment, it also comes with considerations.
So, what should you know about the benefits and risks of HRT? Let’s explore the latest research.
The Benefits: More Than Just Symptom Relief
Many women turn to HRT for relief from menopause symptoms, but its advantages extend far beyond that. Here are some key long-term benefits, backed by research:
Supports Heart Health

– 4 fewer cases of cardiovascular disease per 1,000 women aged 50-59 who start HRT within 10 years of menopause.
– 2.5 fewer deaths per 1,000 women aged 50-59 who initiate body-identical oestradiol (oral or transdermal) with a progestogen.
– No reduction in mortality when HRT is started more than 10 years after menopause with synthetic progestogens.
Stronger Bones & Reduced Fracture Risk
– 7 fewer fractures per 1,000 women aged 50-59 who use HRT.
– 5 fewer fractures per 1,000 women aged 60-69 who take HRT.
– Osteoporosis-related fractures occur in 15 per 1,000 women aged 50-59 each year, highlighting the role of HRT in prevention.
Brain Health & Dementia Risk Reduction

– 14.5 fewer cases of dementia per 1,000 women who start oestrogen-only HRT within 10 years of menopause.
– 10 fewer cases per 1,000 women who start combined oestrogen + progestogen HRT within 10 years of menopause.
– Dementia is a leading cause of death in women, and HRT may play a role in reducing neurodegenerative risks.
May Lower the Risk of Type 2 Diabetes
– 20% of women aged 60-69 have diabetes, and HRT has been linked to improved blood sugar control.
– Women who used HRT for 2.5 to 5 years had a 69% lower risk of developing diabetes.
The Risks: What to Consider
HRT isn’t one-size-fits-all, and certain factors should be considered before starting treatment:
Breast Cancer Risk
– 23 cases of breast cancer per 1,000 women aged 50-59 over five years.
– No increased breast cancer risk has been confirmed for women using body-identical progesterone, but more long-term data is needed.
Blood Clots (VTE – Venous Thromboembolism)
– 5 cases per 1,000 women aged 50-59 using HRT over five years.
– 8 cases per 1,000 women aged 60-69 using HRT over five years.
– No increased risk for women using transdermal oestrogen with or without body-identical progesterone.
Stroke Risk
– 4 cases per 1,000 women aged 50-59 each year.
– 9 cases per 1,000 women aged 60-69 each year.
– No additional stroke risk for women under 60 using transdermal oestrogen.
Finding the Right Approach

The key to HRT is personalization—the right type, dosage, and timing make all the difference. If you’re considering HRT, consult a healthcare professional to explore options that align with your individual health needs.
HRT is not just about managing menopause—it’s about long-term health and quality of life. Whether you’re just starting your research or considering treatment, staying informed empowers you to make the best decisions for your well-being.
Have questions or experiences with HRT? I’d love to hear your thoughts! Let’s keep the conversation going.
WRITTEN BY Dr Anna Ord, Menopause Doctor

Dr Anna is passionate about helping women with their perimenopause and menopause journey. She dedicates each Monday to assisting women at Drift Wellness Centre in Clarkson, and also via online appointments during the week. You can find out more about Dr Anna and book in your appointment on her website www.drannaord.com














